群馬大学神経科学グループ 脳研究統合フォーラム
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先端科学研究指導者育成ユニット

先端医学・生命科学研究チーム

Axonal localization of Ca2+-dependent activator protein for secretion 2 is critical for subcellular locality of brain-derived neurotrophic factor and neurotrophin-3 release affecting proper development of postnatal mouse cerebellum

Tetsushi Sadakata, Wataru Kakegawa, Yo Shinoda, Mayu Hosono, Ritsuko Katoh-Semba, Yukiko Sekine, Yumi Sato, Chihiro Saruta, Yasuki Ishizaki, Michisuke Yuzaki, Masami Kojima, Teiichi Furuichi

PLoS ONE. in press.

 

Mouse Models of Mutations and Variations in Autism Spectrum Disorder-Associated Genes: Mice Expressing Caps2/Cadps2 Copy Number and Alternative Splicing Variants

Tetsushi Sadakata, Yo Shinoda, Akira Sato, Hirotoshi Iguchi, Chiaki Ishii, Makoto Matsuo, Ryosuke Yamaga, Teiichi Furuichi

International Journal of Environmental Research and Public Health. 10 (12), p6335-6353 (2013) (IF: 1.998)

 

CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain.

Tetsushi Sadakata, Wataru Kakegawa, Yo Shinoda, Mayu Hosono, Ritsuko Katoh-Semba, Yukiko Sekine, Yumi Sato, Mika Tanaka, Takuji Iwasato, Shigeyoshi Itohara, Kenichiro Furuyama, Yoshiya Kawaguchi, Yasuki Ishizaki, Michisuke Yuzaki, Teiichi Furuichi

Journal of Neuroscience. 33 (44), p17326-17334 (2013) (IF: 6.908)

 *Both Drs. Sadakata and Furuichi are corresponding authors.

 

Animal Models of Autism Spectrum Disorder (ASD): A Synaptic-Level Approach to Autistic-Like Behavior in Mice

Yo Shinoda, Tetsushi Sadakata, Teiichi Furuichi

Experimental Animals. 62 (2), p71-78 (2013) (IF: 1.456)

 

Autistic-like behavioral phenotypes in a mouse model with copy number variation of the CAPS2/CADPS2 gene

Tetsushi Sadakata, Yo Shinoda, Megumi Oka, Yukiko Sekine, Teiichi Furuichi.

FEBS Letter. 587(1), p54-59 (2013) (IF: 3.478)

 *Both Drs. Sadakata and Furuichi are corresponding authors.

 

Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice.

Tetsushi Sadakata, Yo Shinoda, Megumi Oka, Yukiko Sekine, Yumi Sato, Chihiro Saruta, Hideki Miwa, Mika Tanaka, Shigeyoshi Itohara, Teiichi Furuichi

Proceedings of the National Academy of Sciences of the United States of America. 109 (51), p21104-21109 (2012) (IF: 9.737)

 *Both Drs. Sadakata and Furuichi are corresponding authors.

 

Calcium-dependent activator protein for secretion 2 (CAPS2) interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.

Tetsushi Sadakata, Yukiko Sekine, Megumi Oka, Makoto Itakura, Masami Takahashi, Teiichi Furuichi.

FEBS Journal. 279(3), p384-394 (2012) (IF: 4.250)

 

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